Les Dogues sensationally dethroned PSG last month, but head coach Christophe Galtier stepped down after they were crowned champions.
Lille are yet to appoint a successor to Galtier and whoever the new boss is will take the champions to Metz on the weekend of August 8.
They will face Rennes on the final day of the campaign and come up against PSG for the first time at the Parc des Princes on October 31 before facing Mauricio Pochettino’s side at home on February 6.
? We begin the defence of our #Ligue1 title with a trip to @FCMetz on the weekend of 8 August ?
Goals from @yilmazburak17 & @mzekicelik17 helped us to a 2-0 win on our last visit to Stade Saint-Symphorien. pic.twitter.com/t0SugWaheT
— LOSC Lille EN (@LOSC_EN) June 25, 2021
PSG are also on the road in their first match and finish the season at home to Metz on May 21.
Monaco, who finished third last season, will be at home to Nantes in their opening match and Lyon entertain Brest, with Marseille at Montpellier.
PSG will have home advantage when they face Monaco for the first time next season in a match scheduled for December 12, then travel to the Principality on March 20.
Clermont face an away encounter with Bordeaux first after going up along with Ligue 2 champions Troyes.
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