The number 12 was quickest out the blocks in FP1 before the rain came down in the final few minutes, and with conditions remaining damp in FP2 he remained the fastest on Friday.
FIM MotoGP reigning Champion Joan Mir of Team Suzuki Ecstar was in close attendance, however, 0.080sec off the top as he prepares to make his 100th Grand Prix start on Sunday, with MotorLand winner Francesco Bagnaia (Ducati Lenovo Team) starting his home GP in third.
San Marino GP: Bagnaia leads the cavalry on to Misano
MotoGP will see wheels back on the ground on Saturday morning for FP3. Make sure you tune in for it at 9.55am local time (1.25pm IST).
Qualifying then start from 2.10pm local time (5.40pm IST) with the grid for a pivotal race in the title fight sure to prove hard-fought.
Top 10 combined:
1. Maverick Vinales (Aprilia Racing Team Gresini) – 1:32.666
2. Joan Mir (Team Suzuki Ecstar) + 0.080
3. Francesco Bagnaia (Ducati Lenovo Team) + 0.135
4. Jack Miller (Ducati Lenovo Team) + 0.193
5. Alex Rins (Team Suzuki Ecstar) + 0.219
6. Pol Espargaro (Repsol Honda Team) + 0.353
7. Fabio Quartararo (Monster Energy Yamaha MotoGP) + 0.358
8. Stefan Bradl (Repsol Honda Team) + 0.381
9. Marc Marquez (Repsol Honda Team) + 0.434
10. Aleix Espargaro (Aprilia Racing Team Gresini) + 0.436
(By a special arrangement with Dorna Sports)
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