Monday Night Football FanDuel Picks: NFL DFS lineup advice for Week 6 Bills-Titans single-game tournaments

It was almost a year ago to the day when the Titans handed the Bills their first loss of the season in a 42-16 blowout in a rare edition of “Tuesday Night Football.” The odds of that happening in Week 6 on Monday Night Football are slim, as Buffalo is expected to win with relative ease, opening as five-point road favorites at several online sportsbooks. Even with that said, we have a good mix of Bills and Titans in our FanDuel single game lineup because we all know viable DFS picks can come from anywhere in one-off DFS contests.

Here’s a reminder of FanDuel’s scoring system for single-game contests: The point total for the “MVP” is multiplied by 1.5, but he doesn’t cost any additional money like the “Captain” in DraftKings Showdown contests. FanDuel’s default scoring is half-point PPR and four-point passing TDs, and there are no bonuses for 300-yard/100-yard games like on DraftKings. 

MORE FD SINGLE GAME: How to win a FanDuel single-game contest

FanDuel Single Game DFS Picks: Bills vs. Titans

$60,000 budget, need at least one player from each team 

MVP (1.5x points): QB Josh Allen, Bills ($17,000)

Allen sputtered out of the gate with a pair of sub-20-point performances, but he flirted with the 40-point plateau in two of his past three contests. Another big point total is in order against a less-than-stellar Titans pass defense, making Allen an easy call as our MVP.

FLEX: RB Derrick Henry, Titans ($15,000)

If there’s such a thing as a player being “matchup proof,” Henry certainly qualifies. Buffalo’s defense has played as well or better than any team in the league thus far, and they’ll be keyed in on the reigning two-time rushing champ. That’s enough reason to fade Henry, though. He was limited to 63 total yards in the Titans’ 2020 victory over the Bills, but he still found paydirt twice.

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FLEX: WR Stefon Diggs, Bills ($12,500)

It’s been No. 2 wide receiver Emmanuel Sanders who has hogged touchdowns, scoring four times compared once for Diggs. Diggs, however, does still lead the team with 47 targets while averaging 13.4 yards per reception. It’s all going to click for Diggs sooner rather than later, and we’re going to be all over him as long as his price tag is relatively low.

FLEX: TE Dawson Knox, Bills ($9,000)

Knox has increased his scoring output in each week this season, culminating in 19.2 FanDuel points in the Bills’ Week 5 win over the Chiefs. He’s scored five touchdowns over his past four games, and while we can’t expect that streak to last, we’re going to ride the hot hand in this spot. Knox is doing more than just scoring touchdowns, though. He’s fourth on the team in targets (24) and receptions (18), and he’s averaging a robust 14.5 yards per catch.

FLEX: TE Anthony Firkser, Titans ($6,000)

We’re going to roll the dice with Firkser here, mostly for salary purposes but also because we’re hunting for a cheap score. Not only do the Bills give up the second fewest points to wide receivers, but A.J. Brown (illness) and Julio Jones (hamstring) aren’t likely to handle full workloads as they inch their way back toward full health. Firkser has earned 13 targets in three games and reeled in three grabs in each contest. Modest numbers to say the least, but he leads Titans tight ends despite playing two fewer games than the rest. Finally, there is often a score or two by ancillary pieces in these standalone slates, and Firkser isn’t a bad bet to notch one.